Detorubicin hydrochloride

Overview

Detorubicin hydrochloride (NSC 292652 hydrochloride) is a semi-synthetic analog of Daunorubicin ( HY-13062A ) and a prodrug of Doxorubicin ( HY-15142A ). Detorubicin hydrochloride hydrolyzes to release Doxorubicin under neutral pH conditions. Detorubicin hydrochloride forms complexes with DNA . Detorubicin hydrochloride exhibits anti-hematologic tumor and metastatic melanoma activities. Detorubicin hydrochloride causes myocardial injury, skin damage, alopecia, and high mortality in golden hamsters. Detorubicin hydrochloride can be used in research related to leukemia, and metastatic melanoma.

Application

Products | Products > Disease Areas > Blood Disease | Products > Disease Areas > Heart Disease | Products > Disease Areas > Metastatic Melanoma | Products > Disease Areas > Cancer | Products > Disease Areas > Blood or Cardio-cerebrovascular Disease | Products > Disease Areas > Melanoma | Products > Disease Areas > Leukemia/Lymphoma/Myeloma | Products > Signaling Pathways > Others | Products > Signaling Pathways > Cell Cycle/DNA Damage | Products > Research Areas > Cardiovascular Disease | Products > Research Areas > Cancer | Products > Research Areas > Cancer > Cancer Metabolism and Metastasis | Products > Signaling Pathways > Drug Derivative | Products > Signaling Pathways > DNA Alkylator/Crosslinker

Product Information

• Catalog No.: HY-106414A
• CAS No.: 64291-45-8
• Molecular Formula: C33H40ClNO14
• Molecular Weight: 710.12
• Storage: Please store the product under the recommended conditions in the Certificate of Analysis.

Source

Original product source