2C07

Overview

2C07 is a mutant Ras ( K-Ras M72C , H-Ras M72C ) inhibitor. 2C07 blocks the activation of PI3K through allosteric Ras modification. 2C07 binds to the modified switch II pocket (S-IIG) of Ras in both GDP- and GTP-bound states, stabilizes the GDP-bound state, disrupts the polar interactions of the canonical GTP-bound state, and inhibits SOS binding and nucleotide exchange. 2C07 can be used in cancer-related research.

Application

Products | Products > Disease Areas > Cancer | Products > Signaling Pathways > GPCR/G Protein | Products > Signaling Pathways > MAPK/ERK Pathway | Products > Signaling Pathways > PI3K/Akt/mTOR | Products > Research Areas > Cancer > Cancer Targeted Therapy | Products > Research Areas > Cancer > Cancer Metabolism and Metastasis | Products > Research Areas > Cancer | Products > Signaling Pathways > Ras | Products > Signaling Pathways > PI3K | Products > Signaling Pathways > SOS1

Product Information

• Catalog No.: HY-114894
• CAS No.: 2230185-95-0
• Molecular Formula: C19H25F3N4O2S2
• Molecular Weight: 462.55
• Storage: Please store the product under the recommended conditions in the Certificate of Analysis.

Source

Original product source