EGFR-IN-451

Overview

EGFR-IN-451 is an EGFR inhibitor with an IC 50 value of 0.02 nM. EGFR-IN-451 also inhibits mutant EGFR L858R , EGFR T790M , and EGFR L858R/T790M with IC 50 values of 0.26-34 nM. EGFR-IN-451 inhibits AKT and ERK activation and inhibits proliferation of EGFR-mutant cancer cells. EGFR-IN-451 can be used for the research of EGFR-driven cancer .

Application

Products | Products > Disease Areas > Cancer | Products > Signaling Pathways > JAK/STAT Signaling | Products > Signaling Pathways > Protein Tyrosine Kinase/RTK | Products > Signaling Pathways > PI3K/Akt/mTOR | Products > Signaling Pathways > MAPK/ERK Pathway | Products > Signaling Pathways > Stem Cell/Wnt | Products > Research Areas > Cancer | Products > Research Areas > Cancer > Cancer Targeted Therapy | Products > Research Areas > Cancer > Cancer Stem Cells | Products > Research Areas > Cancer > Cancer Metabolism and Metastasis | Products > Signaling Pathways > EGFR | Products > Signaling Pathways > Akt | Products > Signaling Pathways > ERK

Product Information

• Catalog No.: HY-116091
• CAS No.: 220576-72-7
• Molecular Formula: C19H15N5O
• Molecular Weight: 329.36
• Storage: Please store the product under the recommended conditions in the Certificate of Analysis.

Source

Original product source