CPI-644

Overview

CPI-644 is a selective EP300/CBP bromodomain inhibitor, with an IC 50 of 0.18 µM against the CBP bromodomain. CPI-644 reduces the proportion of FOXP3 + cells and downregulates the expression of LAG-3 , CTLA-4 and PD-1 . CPI-644 can be used in cancer-related research.

Application

Products | Products > Disease Areas > Cancer | Products > Signaling Pathways > Epigenetics | Products > Signaling Pathways > Immunology/Inflammation | Products > Research Areas > Cancer > Cancer Targeted Therapy | Products > Research Areas > Cancer > Cancer Immunotherapy | Products > Research Areas > Cancer > Cancer Metabolism and Metastasis | Products > Research Areas > Cancer | Products > Signaling Pathways > Histone Acetyltransferase | Products > Signaling Pathways > LAG-3 | Products > Signaling Pathways > CTLA-4 | Products > Signaling Pathways > PD-1/PD-L1

Product Information

• Catalog No.: HY-122081
• CAS No.: 1904647-34-2
• Molecular Formula: C18H19N3O3S
• Molecular Weight: 357.43
• Storage: Please store the product under the recommended conditions in the Certificate of Analysis.

Source

Original product source