CRT0093964 is an isoform-selective non-carboxylate inhibitor of AKR1C3 ( IC 50 =0.11 μM) with no activity against AKR1C1 , AKR1C2 , AKR1C4 , COX-1 , and COX-2 .CRT0093964 can be used for the research of leukemia, hormone-related cancers, colon cancer .
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