Linichlorin A

Overview

Linichlorin A is a p27 Kip1 ubiquitination inhibitor that blocks p27 Kip1 degradation by inhibiting the Skp2-Cks1–p27 Kip1 interaction. Linichlorin A shows selective antiproliferative activity against tumor cells. Linichlorin A induces apoptosis in leukemia cells via cytochrome c release, caspase activation and PARP cleavage. Linichlorin A can be used in the study of leukemia, melanoma, cervical cancer and breast cancer .

Application

Products | Products > Disease Areas > Urogenital Disease | Products > Disease Areas > Breast Cancer | Products > Disease Areas > Cervical Cancer | Products > Disease Areas > Urogenital Cancer | Products > Disease Areas > Melanoma | Products > Disease Areas > Blood Disease | Products > Disease Areas > Cancer | Products > Disease Areas > Blood or Cardio-cerebrovascular Disease | Products > Signaling Pathways > Apoptosis | Products > Signaling Pathways > Epigenetics | Products > Signaling Pathways > Cell Cycle/DNA Damage | Products > Research Areas > Cancer | Products > Research Areas > Cancer > Cancer Targeted Therapy | Products > Research Areas > Cancer > Cancer Metabolism and Metastasis | Products > Signaling Pathways > Caspase | Products > Signaling Pathways > Apoptosis | Products > Signaling Pathways > PARP

Product Information

• Catalog No.: HY-126757
• CAS No.: 62462-98-0
• Molecular Formula: C19H23ClO6
• Molecular Weight: 382.84
• Storage: Please store the product under the recommended conditions in the Certificate of Analysis.

Source

Original product source