Sabarubicin hydrochloride (MEN 10755 hydrochloride) is a disaccharide analog of Doxorubicin ( HY-15142A ). Sabarubicin hydrochloride stimulates topoisomerase II-mediated DNA cleavage, induces DNA strand breaks and Apoptosis . Sabarubicin hydrochloride binds to and stabilizes telomeric G-quadruplex DNA. Sabarubicin hydrochloride is applicable to research related to ovarian tumors, breast cancer and lung cancer .
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