EGFR-IN-59

Overview

EGFR-IN-59 (Compound 8c) is a EGFR inhibitor ( IC 50 =190 nM) and apoptosis inducer. EGFR-IN-59 exhibits cytotoxicity against non-small lung cancer cell lines (A549) and normal lung fibroblasts (WI38) with IC 50 s of 8.62 and 52.6 µM, respectively. EGFR-IN-59 can be used for the research of various cancers such as non-small cell lung cancer (NSCLC), head and neck cancer , breast cancer and colorectal cancer .

Application

Products | Products > Signaling Pathways > JAK/STAT Signaling | Products > Signaling Pathways > Protein Tyrosine Kinase/RTK | Products > Signaling Pathways > Apoptosis | Products > Research Areas > Cancer | Products > Research Areas > Cancer > Cancer Targeted Therapy | Products > Research Areas > Cancer > Cancer Metabolism and Metastasis | Products > Signaling Pathways > EGFR | Products > Signaling Pathways > Apoptosis

Product Information

• Catalog No.: HY-147802
• CAS No.: 2529891-44-7
• Molecular Formula: C27H23N5O4S
• Molecular Weight: 513.57
• Storage: Please store the product under the recommended conditions in the Certificate of Analysis.

Source

Original product source