ZSTK3744

Overview

ZSTK3744 is an aryl hydrocarbon receptor ( AhR ) agonist. ZSTK3744 directly binds to AhR , upregulates the expression of AhR target genes including CYP1A1 , CYP1B1 and TIPARP , and mediates cell growth inhibitory activity in triple-negative breast cancer cells. ZSTK3744 induces apoptosis in triple-negative breast cancer cells. ZSTK3744 exhibits anti-tumor activity and can be used in the research of chemoresistant triple-negative breast cancer .

Application

Products | Products > Disease Areas > Breast Cancer | Products > Disease Areas > Triple-Negative Breast Cancer | Products > Disease Areas > Cancer | Products > Signaling Pathways > Immunology/Inflammation | Products > Signaling Pathways > Apoptosis | Products > Signaling Pathways > Metabolic Enzyme/Protease | Products > Research Areas > Cancer | Products > Research Areas > Cancer > Cancer Targeted Therapy | Products > Research Areas > Cancer > Cancer Immunotherapy | Products > Research Areas > Cancer > Cancer Drug Resistance | Products > Research Areas > Cancer > Cancer Metabolism and Metastasis | Products > Signaling Pathways > Aryl Hydrocarbon Receptor | Products > Signaling Pathways > Apoptosis | Products > Signaling Pathways > Caspase | Products > Signaling Pathways > Cytochrome P450

Product Information

• Catalog No.: HY-181629
• CAS No.: 3106975-38-3
• Molecular Formula: C22H19N7
• Molecular Weight: 381.43
• Storage: Please store the product under the recommended conditions in the Certificate of Analysis.

Source

Original product source