CAIX Inhibitor S4

Overview

CAIX Inhibitor S4 is a potent and selective inhibitor of carbonic anhydrase IX/XII ( CA IX/XII) , with a K i of 7 nM and 2 nM, respectively. CAIX Inhibitor S4 also inhibits CA II and CA I ( K i =546 and 5600 nM, respectively). CAIX Inhibitor S4 can inhibit the number of lung metastasis in orthotopic MDA-MB-231 mouse model without affecting primary tumor growth.

Application

Products | Products > Disease Areas > Cancer | Products > Signaling Pathways > Metabolic Enzyme/Protease | Products > Research Areas > Cancer | Products > Research Areas > Cancer > Cancer Targeted Therapy | Products > Research Areas > Cancer > Cancer Metabolism and Metastasis | Products > Signaling Pathways > Carbonic Anhydrase

Product Information

• Catalog No.: HY-110243
• CAS No.: 1330061-67-0
• Molecular Formula: C15H17N3O4S
• Molecular Weight: 335.38
• Purity: 99.04%
• Storage: Powder -20°C, 3 years , 4°C, 2 years ; In solvent -80°C, 6 months , -20°C, 1 month
• Availability: In-stock

Source

Original product source