ATOX1-IN-1

Overview

ATOX1-IN-1 is an inhibitor of ATOX1 (a copper chaperone protein) with a K d value of 12.5 μM. ATOX1-IN-1 induces intracellular copper accumulation, increases the level of DNA methylation in the NOTCH1 promoter region, and inhibits the NOTCH1/HES1 signaling pathway. ATOX1-IN-1 enhances the sensitivity of hepatocellular carcinoma cells to Cisplatin ( HY-17394 ). ATOX1-IN-1 can be used in hepatocellular carcinoma-related research.

Application

Products | Products > Disease Areas > Cancer | Products > Disease Areas > Digestive System Disease | Products > Disease Areas > Liver Cancer | Products > Disease Areas > Digestive System Cancer | Products > Signaling Pathways > Neuronal Signaling | Products > Signaling Pathways > Stem Cell/Wnt | Products > Research Areas > Cancer > Cancer Targeted Therapy | Products > Research Areas > Cancer > Cancer Stem Cells | Products > Research Areas > Cancer > Cancer Metabolism and Metastasis | Products > Research Areas > Cancer | Products > Signaling Pathways > Notch

Product Information

• Catalog No.: HY-181975
• CAS No.: 956181-19-4
• Molecular Formula: C33H26N2O6
• Molecular Weight: 546.57
• Storage: Please store the product under the recommended conditions in the Certificate of Analysis.

Source

Original product source