HDAC8-IN-16 is a selective histone deacetylase 8 ( HDAC8 ) inhibitor with an IC 50 of 0.16 μM. HDAC8-IN-16 induces cell apoptosis , triggers G 2 /M phase cell cycle arrest, and moderately inhibits cancer cell proliferation. HDAC8-IN-16 is applicable to relevant research on colorectal cancer .
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