ML334

Overview

ML334 is a potent, cell permeable activator of NRF2 by inhibition of Keap1-NRF2 protein-protein interaction. ML334 binds to Keap1 Kelch domain with a K d of 1 μM. ML334 stimulates NRF2 expression and nuclear translocation and induces antioxidant response elements (ARE) activity.

Application

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Product Information

• Catalog No.: HY-110258
• CAS No.: 1432500-66-7
• Molecular Formula: C26H26N2O5
• Molecular Weight: 446.50
• Purity: 98.09%
• Storage: 4°C, stored under nitrogen * In solvent : -80°C, 6 months; -20°C, 1 month (stored under nitrogen)
• Solubility: ≥ 5 mg/mL (11.20 mM); Clear solution
• Availability: In-stock

Source

Original product source