Cathepsin-IN-5 is a cathepsin inhibitor with IC 50 values of 6.2 μM and 81 nM for cathepsin L and cathepsin S . Cathepsin-IN-5 inhibits cancer cells proliferation, induces apoptosis , reduces growth of hepatocellular tumors in mouse models, and modulates expression of genes linked to cell death, cell proliferation, and cellular processes. Cathepsin-IN-5 can be used for the research of hepatocellular carcinoma.
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