BTK-IN-48 is a BTK inhibitor with an IC 50 of 1.14 μM. BTK-IN-48 inhibits recombinant BTK and c-Src , and exerts moderate inhibitory effects on LCK , BMX/ETK , FLT3 and PIM1 . BTK-IN-48 can be used in the research of B-cell malignancies and autoimmune diseases.
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