TMLZ-G46 is an orally active ZNF207 inhibitor with blood-brain barrier penetration ability, with a K d value of 68 nM. TMLZ-G46 inhibits cancer cell proliferation, stemness, migration and invasion, induces G0/G1 cell cycle arrest and apoptosis , and suppresses colony formation. TMLZ-G46 can be used in glioma research.
Products | Products > Disease Areas > Cancer | Products > Disease Areas > Glioma | Products > Signaling Pathways > Apoptosis | Products > Research Areas > Cancer | Products > Research Areas > Cancer > Cancer Targeted Therapy | Products > Research Areas > Cancer > Cancer Stem Cells | Products > Research Areas > Cancer > Cancer Metabolism and Metastasis | Products > Signaling Pathways > Apoptosis
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