NH4-6

Overview

NH4-6 is a SIRT2 inhibitor with an IC 50 of 0.032 μM against SIRT2 and an IC 50 of 3 μM against SIRT1 . NH4-6 inhibits the deacetylase activity of SIRT1 . As a cytotoxic agent, NH4-6 reduces cancer cell viability, suppresses anchorage-independent growth of cancer cells, induces acetylation of α-tubulin , and promotes acetylation of p53 . NH4-6 can be used in the research of breast cancer .

Application

Products | Products > Disease Areas > Cancer | Products > Disease Areas > Breast Cancer | Products > Signaling Pathways > Cell Cycle/DNA Damage | Products > Signaling Pathways > Epigenetics | Products > Research Areas > Cancer > Cancer Metabolism and Metastasis | Products > Research Areas > Cancer | Products > Research Areas > Cancer > Cancer Targeted Therapy | Products > Research Areas > Cancer > Cancer Immunotherapy | Products > Signaling Pathways > Sirtuin

Product Information

• Catalog No.: HY-182412
• CAS No.: 2375182-58-2
• Molecular Formula: C33H59IN4O3S
• Molecular Weight: 718.82
• Storage: Please store the product under the recommended conditions in the Certificate of Analysis.

Source

Original product source