NTZ-24

Overview

NTZ-24 is a selective STAT3 pathway inhibitor. NTZ-24 suppresses STAT3 phosphorylation at Tyr705, blocks STAT3-DNA interaction, and downregulates the levels of STAT3 downstream target proteins. NTZ-24 induces cell-cycle arrest and promotes apoptosis in cancer cells. NTZ-24 exerts significant antiproliferative activity against HeLa cells ( IC 50 = 3.3 μM). NTZ-24 can be used for the research of cervical cancer .

Application

Products | Products > Disease Areas > Urogenital Disease | Products > Disease Areas > Cervical Cancer | Products > Disease Areas > Urogenital Cancer | Products > Disease Areas > Cancer | Products > Signaling Pathways > JAK/STAT Signaling | Products > Signaling Pathways > Stem Cell/Wnt | Products > Signaling Pathways > Immunology/Inflammation | Products > Signaling Pathways > Apoptosis | Products > Research Areas > Cancer | Products > Research Areas > Cancer > Cancer Targeted Therapy | Products > Research Areas > Cancer > Cancer Immunotherapy | Products > Research Areas > Cancer > Cancer Stem Cells | Products > Research Areas > Cancer > Cancer Metabolism and Metastasis | Products > Signaling Pathways > STAT | Products > Signaling Pathways > Interleukin Related | Products > Signaling Pathways > Apoptosis

Product Information

• Catalog No.: HY-182510
• CAS No.: 69819-42-7
• Molecular Formula: C10H5Cl2N3O3S
• Molecular Weight: 318.14
• Storage: Please store the product under the recommended conditions in the Certificate of Analysis.

Source

Original product source