SB-747651A dihydrochloride is an ATP-competitive mitogen- and stress-activated kinase 1 (MSK1) inhibitor with an IC 50 of 11 nM. SB-747651A dihydrochloride also inhibits PRK2, RSK1 , p70S6K and ROCK-II. SB-747651A dihydrochloride can be used for inflammation research.
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