CLR/RAMP3-receptor antagonist-1

Overview

CLR/RAMP3-receptor antagonist-1 is a selective antagonist of the CLR/RAMP3 receptor ( CLR/RAMP3, AM 2 receptor ), with pIC 50 values of 5.86, 9.21 and 9.07 against AM 1 (CLR/RAMP2), AM 2 (CLR/RAMP3) and CGRP (CLR/RAMP1) receptors, respectively. CLR/RAMP3-receptor antagonist-1 reduces the levels of pancreatic cancer progression markers, induces apoptosis in vitro, and prolongs survival in mouse models of pancreatic cancer . CLR/RAMP3-receptor antagonist-1 can be used in pancreatic cancer-related research.

Application

Products | Products > Disease Areas > Cancer | Products > Disease Areas > Digestive System Disease | Products > Disease Areas > Pancreatic Cancer | Products > Disease Areas > Digestive System Cancer | Products > Signaling Pathways > GPCR/G Protein | Products > Signaling Pathways > Neuronal Signaling | Products > Research Areas > Cancer > Cancer Metabolism and Metastasis | Products > Research Areas > Cancer | Products > Signaling Pathways > CGRP Receptor

Product Information

• Catalog No.: HY-183142
• CAS No.: 2252341-45-8
• Molecular Formula: C31H35N5O3
• Molecular Weight: 525.64
• Storage: Please store the product under the recommended conditions in the Certificate of Analysis.
• Availability: In-stock

Source

Original product source