GPX4-IN-24

Overview

GPX4-IN-24 is an orally active glutathione peroxidase 4 ( GPX4 ) inhibitor with a human IC 50 of 10.90 μM, human K d of 10.04 μM. GPX4-IN-24 suppresses GPX4 enzymatic activity, disrupts redox homeostasis, drives lipid peroxidation, promotes lipid peroxidation, and induces ferroptosis . GPX4-IN-24 can be used for the research of triple-negative breast cancer .

Application

Products | Products > Disease Areas > Breast Cancer | Products > Disease Areas > Triple-Negative Breast Cancer | Products > Disease Areas > Cancer | Products > Signaling Pathways > Apoptosis | Products > Signaling Pathways > Metabolic Enzyme/Protease | Products > Signaling Pathways > NF-κB | Products > Signaling Pathways > Immunology/Inflammation | Products > Research Areas > Cancer | Products > Research Areas > Cancer > Cancer Targeted Therapy | Products > Research Areas > Cancer > Cancer Immunotherapy | Products > Research Areas > Cancer > Cancer Metabolism and Metastasis | Products > Signaling Pathways > Glutathione Peroxidase | Products > Signaling Pathways > Ferroptosis | Products > Signaling Pathways > Reactive Oxygen Species (ROS)

Product Information

• Catalog No.: HY-183294
• CAS No.: 2834106-56-6
• Molecular Formula: C31H35N7O4
• Molecular Weight: 569.65
• Storage: Please store the product under the recommended conditions in the Certificate of Analysis.

Source

Original product source