VEGFR/PD-L1-IN-1

Overview

VEGFR/PD-L1-IN-1 is a VEGFR2 and PD-L1 inhibitor, with IC 50 values of 0.383 μM and 134.407 pg/mL against VEGFR2 and PD-L1 , respectively. VEGFR/PD-L1-IN-1 enhances the secretion of INF-γ , induces G0/G1 cell cycle arrest in cancer cells, and triggers cancer cell apoptosis . VEGFR/PD-L1-IN-1 upregulates the expression of BAX and Caspase-3 , and downregulates the expression of Bcl-2 . VEGFR/PD-L1-IN-1 can be used in research related to hepatocellular carcinoma, prostate cancer , and colorectal cancer .

Application

Products | Products > Disease Areas > Cancer | Products > Disease Areas > Digestive System Disease | Products > Disease Areas > Urogenital Disease | Products > Disease Areas > Colorectal Cancer | Products > Disease Areas > Digestive System Cancer | Products > Disease Areas > Prostate Cancer | Products > Disease Areas > Urogenital Cancer | Products > Disease Areas > Liver Cancer | Products > Signaling Pathways > Protein Tyrosine Kinase/RTK | Products > Signaling Pathways > Immunology/Inflammation | Products > Signaling Pathways > Apoptosis | Products > Research Areas > Cancer | Products > Research Areas > Cancer > Cancer Targeted Therapy | Products > Research Areas > Cancer > Cancer Immunotherapy | Products > Research Areas > Cancer > Cancer Metabolism and Metastasis | Products > Signaling Pathways > VEGFR | Products > Signaling Pathways > PD-1/PD-L1 | Products > Signaling Pathways > Apoptosis | Products > Signaling Pathways > Bcl-2 Family | Products > Signaling Pathways > Caspase

Product Information

• Catalog No.: HY-183369
• CAS No.: 2675913-94-5
• Molecular Formula: C21H18N6O4
• Molecular Weight: 418.41
• Storage: Please store the product under the recommended conditions in the Certificate of Analysis.

Source

Original product source