AUBE00

Overview

AUBE00 is an orally active, selective cyclic peptide pan- KRAS inhibitor. AUBE00 selectively binds to the OFF state of KRAS. AUBE00 exhibits anticancer activity against RAS wild-type colorectal cancer . The combination of AUBE00 with Cetuximab ( HY-P9905 ) produces a synergistic antiproliferative effect.

Application

Products | Products > Disease Areas > Cancer | Products > Disease Areas > Digestive System Disease | Products > Disease Areas > Colorectal Cancer | Products > Disease Areas > Digestive System Cancer | Products > Signaling Pathways > GPCR/G Protein | Products > Signaling Pathways > MAPK/ERK Pathway | Products > Research Areas > Cancer > Cancer Targeted Therapy | Products > Research Areas > Cancer > Cancer Metabolism and Metastasis | Products > Research Areas > Cancer | Products > Signaling Pathways > Ras

Product Information

• Catalog No.: HY-183553
• CAS No.: 2874214-01-2
• Molecular Formula: C78H110F6N12O14
• Molecular Weight: 1553.77
• Storage: Please store the product under the recommended conditions in the Certificate of Analysis.

Source

Original product source