MK-1088

Overview

MK-1088 is an orally active A 2A /A 2B adenosine receptor antagonist with human A 2A K i of 0.31 nM, human A 2B K i 5.3 nM. MK-1088 blocks receptor downstream signaling, inhibits CREB phosphorylation and reverses adenosine-mediated immunosuppression. MK-1088 restores TNF−α release and enhances tumor immune surveillance. MK-1088 can be used for the research of cancer [1] .

Application

Products | Products > Disease Areas > Cancer | Products > Signaling Pathways > GPCR/G Protein | Products > Research Areas > Cancer | Products > Research Areas > Cancer > Cancer Targeted Therapy | Products > Research Areas > Cancer > Cancer Immunotherapy | Products > Research Areas > Cancer > Cancer Metabolism and Metastasis | Products > Signaling Pathways > Adenosine Receptor

Product Information

• Catalog No.: HY-183599
• CAS No.: 2433765-51-4
• Molecular Formula: C23H29FN8O2
• Molecular Weight: 468.53
• Storage: Please store the product under the recommended conditions in the Certificate of Analysis.

Source

Original product source