T-10531

Overview

T-10531 is a selective USP25 / USP28 inhibitor. T-10531 exhibits an IC 50 of 0.03 μM and a K d of 0.2 μM against human USP25, as well as an IC 50 of 0.12 μM and a K d of 0.06 μM against human USP28. T-10531 inhibits USP25/USP28 activity and induces the degradation of USP25 via the proteasomal pathway, without inhibiting other deubiquitinases. T-10531 can be used in the research of squamous cell carcinoma, colorectal cancer , gastric cancer , triple-negative breast cancer and pancreatic cancer .

Application

Products | Products > Disease Areas > Cancer | Products > Signaling Pathways > Cell Cycle/DNA Damage | Products > Research Areas > Cancer | Products > Research Areas > Cancer > Cancer Targeted Therapy | Products > Research Areas > Cancer > Cancer Metabolism and Metastasis | Products > Signaling Pathways > Deubiquitinase

Product Information

• Catalog No.: HY-183604
• CAS No.: 3129176-25-3
• Molecular Formula: C26H22BrClF4N2O5S
• Molecular Weight: 665.88
• Storage: Please store the product under the recommended conditions in the Certificate of Analysis.

Source

Original product source