CQ31

Overview

CQ31 is a PEPD and XPNPEP1 inhibitor, with an IC 50 of 0.67 μM against PEPD and an IC 50 of 122 μM against XPNPEP1 . CQ31 inhibits the M24B aminopeptidase activity of PEPD and XPNPEP1 . CQ31 induces the accumulation of Xaa-Pro-containing peptides, mildly inhibits DPP8/9 , and triggers CASP1 -dependent pyroptosis via activation of the CARD8 inflammasome and caspase-1 . CQ31 can be used in research related to cancers such as acute myeloid leukemia.

Application

Products | Products > Disease Areas > Acute Myeloid Leukemia | Products > Disease Areas > Cancer | Products > Disease Areas > Blood or Cardio-cerebrovascular Disease | Products > Disease Areas > Leukemia/Lymphoma/Myeloma | Products > Disease Areas > Blood Disease | Products > Signaling Pathways > Apoptosis | Products > Signaling Pathways > Immunology/Inflammation | Products > Research Areas > Cancer | Products > Research Areas > Cancer > Cancer Targeted Therapy | Products > Research Areas > Cancer > Cancer Immunotherapy | Products > Research Areas > Cancer > Cancer Metabolism and Metastasis | Products > Signaling Pathways > Pyroptosis | Products > Signaling Pathways > Caspase

Product Information

• Catalog No.: HY-183739
• CAS No.: 441022-67-9
• Molecular Formula: C13H24N2O4
• Molecular Weight: 272.34
• Storage: Please store the product under the recommended conditions in the Certificate of Analysis.

Source

Original product source