CGP-74514 dihydrochloride is a highly selective cyclin-dependent kinase 1 ( CDK1 ) inhibitor ( IC 50 =25 nM). CGP-74514 dihydrochloride inhibits CDK1/cyclin B complex activity, arrests the cell cycle at G 2 /M phase and induces tumor cell apoptosis . CGP-74514 dihydrochloride is promising for research of bladder cancer .
Products | Products > Signaling Pathways > Cell Cycle/DNA Damage | Products > Signaling Pathways > Apoptosis | Products > Research Areas > Cancer | Products > Research Areas > Cancer > Cancer Targeted Therapy | Products > Research Areas > Cancer > Cancer Metabolism and Metastasis | Products > Signaling Pathways > CDK | Products > Signaling Pathways > Apoptosis
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