AG-12286

Overview

AG-12286 is a pan- CDK inhibitor with an IC 50 value of 2 nM against cdk1/cyclin B , 6 nM against cdk2/cyclin E , and 12 nM against cdk4/cyclin D . AG-12286 is 1000-fold more selective for the CDK family than for PKC . AG-12286 can be used in cancer research.

Application

Products | Products > Disease Areas > Cancer | Products > Signaling Pathways > Cell Cycle/DNA Damage | Products > Research Areas > Cancer | Products > Research Areas > Cancer > Cancer Targeted Therapy | Products > Research Areas > Cancer > Cancer Metabolism and Metastasis | Products > Signaling Pathways > CDK

Product Information

• Catalog No.: HY-183854
• CAS No.: 223784-75-6
• Molecular Formula: C16H12F2N4O3S2
• Molecular Weight: 410.42
• Storage: Please store the product under the recommended conditions in the Certificate of Analysis.

Source

Original product source