LC1236

Overview

LC1236 is a thymidylate synthase ( hTS ) dimer dissociator with a target K d of 7 μM and poor transmembrane permeability. LC1236 inhibits enzymatic activity by shifting the monomer-dimer equilibrium toward inactive monomers. LC1236 acts as a cytotoxic agent to inhibit cancer cell growth, and exerts synergistic cytotoxicity with electroporation via enhancing intracellular accumulation. LC1236 can be used in the research of cancers such as ovarian cancer and colorectal cancer .

Application

Products | Products > Disease Areas > Cancer | Products > Signaling Pathways > Apoptosis | Products > Research Areas > Cancer | Products > Research Areas > Cancer > Cancer Targeted Therapy | Products > Research Areas > Cancer > Cancer Drug Resistance | Products > Research Areas > Cancer > Cancer Metabolism and Metastasis | Products > Signaling Pathways > Thymidylate Synthase

Product Information

• Catalog No.: HY-184154
• CAS No.: 2756347-47-2
• Molecular Formula: C21H16N2O5S
• Molecular Weight: 408.43
• Storage: Please store the product under the recommended conditions in the Certificate of Analysis.

Source

Original product source