Bcl-2-IN-26

Overview

Bcl-2-IN-26 is an inhibitor targeting β-tubulin and BCL-2 . Bcl-2-IN-26 disrupts the intracellular microtubule network and interferes with cell mitosis , inducing G2/M phase cell cycle arrest. Bcl-2-IN-26 suppresses antiapoptotic BCL-2 function via p53 upregulation, thereby triggering mitochondrial dysfunction , elevated ROS production and robust tumor cell apoptosis . Bcl-2-IN-26 can be used in lung cancer research.

Application

Products | Products > Disease Areas > Cancer | Products > Disease Areas > Lung Cancer | Products > Signaling Pathways > Cell Cycle/DNA Damage | Products > Signaling Pathways > Cytoskeleton | Products > Signaling Pathways > Apoptosis | Products > Signaling Pathways > Metabolic Enzyme/Protease | Products > Signaling Pathways > NF-κB | Products > Signaling Pathways > Immunology/Inflammation | Products > Research Areas > Cancer | Products > Research Areas > Cancer > Cancer Targeted Therapy | Products > Research Areas > Cancer > Cancer Immunotherapy | Products > Research Areas > Cancer > Cancer Metabolism and Metastasis | Products > Signaling Pathways > Apoptosis | Products > Signaling Pathways > MDM-2/p53 | Products > Signaling Pathways > Mitochondrial Metabolism | Products > Signaling Pathways > Reactive Oxygen Species (ROS) | Products > Signaling Pathways > Microtubule/Tubulin | Products > Signaling Pathways > Bcl-2 Family

Product Information

• Catalog No.: HY-184443
• CAS No.: 3119834-80-6
• Molecular Formula: C20H16F2N2O4
• Molecular Weight: 386.35
• Storage: Please store the product under the recommended conditions in the Certificate of Analysis.

Source

Original product source