CIB-Q22

Overview

CIB-Q22 is a potent pyruvate carboxylase ( PC ) inhibitor with an IC 50 of 1.74 nM. CIB-Q22 suppresses hepatocellular carcinoma (HCC) cell proliferation, migration, and invasion. CIB-Q22 induces apoptosis and ferroptosis , promotes mitochondrial oxidative stress and dysfunction, inhibits glycolysis and anaplerotic flux, and reverses epithelial-mesenchymal transition (EMT). CIB-Q22 can be used for the study of hepatocellular carcinoma.

Application

Products | Products > Disease Areas > Cancer | Products > Disease Areas > Digestive System Disease | Products > Disease Areas > Liver Cancer | Products > Disease Areas > Digestive System Cancer | Products > Signaling Pathways > Metabolic Enzyme/Protease | Products > Signaling Pathways > Apoptosis | Products > Signaling Pathways > Epigenetics | Products > Signaling Pathways > Cell Cycle/DNA Damage | Products > Research Areas > Cancer | Products > Research Areas > Cancer > Cancer Targeted Therapy | Products > Research Areas > Cancer > Cancer Metabolism and Metastasis | Products > Signaling Pathways > Bcl-2 Family | Products > Signaling Pathways > PARP | Products > Signaling Pathways > Glutathione Peroxidase | Products > Signaling Pathways > Pyruvate Carboxylase (PC) | Products > Signaling Pathways > Apoptosis | Products > Signaling Pathways > Ferroptosis | Products > Signaling Pathways > Caspase

Product Information

• Catalog No.: HY-184448
• CAS No.: 2963747-43-3
• Molecular Formula: C18H22FNO4
• Molecular Weight: 335.37
• Storage: Please store the product under the recommended conditions in the Certificate of Analysis.

Source

Original product source