YL-602

Overview

YL-602 is an orally active Hippo pathway activator. YL-602 activates the Hippo pathway via MST1/2 , with downstream pathway activation. YL-602 inhibits YAP and CTGF expression in cells irrespective of cell density and serum presence. YL-602 induces tumor cell apoptosis and inhibits colony formation. YL-602 suppresses tumor growth in mice. YL-602 can be used for the research of cancer , such as breast cancer .

Application

Products | Products > Disease Areas > Cancer | Products > Disease Areas > Breast Cancer | Products > Signaling Pathways > Stem Cell/Wnt | Products > Signaling Pathways > Apoptosis | Products > Research Areas > Cancer > Cancer Stem Cells | Products > Research Areas > Cancer > Cancer Metabolism and Metastasis | Products > Research Areas > Cancer | Products > Signaling Pathways > Hippo (MST) | Products > Signaling Pathways > YAP | Products > Signaling Pathways > Apoptosis

Product Information

• Catalog No.: HY-186148
• CAS No.: 3081701-84-7
• Molecular Formula: C17H11NO4
• Molecular Weight: 293.27
• Storage: Please store the product under the recommended conditions in the Certificate of Analysis.

Source

Original product source