N-Myc-IN-1

Overview

N-Myc-IN-1 is a selective N-Myc inhibitor/degrader with a K d value of 1.47 μM. N-Myc-IN-1 promotes phosphorylation of N-Myc at threonine-58, triggers N-Myc degradation via the ubiquitin-proteasome pathway, and suppresses the expression of N-Myc target genes. N-Myc-IN-1 reduces the viability of MYCN-dependent tumor cells and induces apoptosis . N-Myc-IN-1 can be used in the research of neuroblastoma.

Application

Products | Products > Disease Areas > Cancer | Products > Disease Areas > Neurological, Eye or Ear Disease | Products > Disease Areas > Neuroblastoma | Products > Disease Areas > CNS Neoplasm | Products > Signaling Pathways > Apoptosis | Products > Research Areas > Cancer | Products > Research Areas > Cancer > Cancer Targeted Therapy | Products > Research Areas > Cancer > Cancer Metabolism and Metastasis | Products > Research Areas > Neurological Disease | Products > Signaling Pathways > c-Myc | Products > Signaling Pathways > Apoptosis

Product Information

• Catalog No.: HY-186247
• CAS No.: 885986-52-7
• Molecular Formula: C15H13BrN4O2
• Molecular Weight: 361.19
• Storage: Please store the product under the recommended conditions in the Certificate of Analysis.

Source

Original product source