Siremadlin succinate

Overview

Siremadlin (NVP-HDM201) succinate is an MDM2 inhibitor and cell cycle regulator. Siremadlin succinate blocks the p53-binding pocket of MDM2 , inhibits MDM2-mediated ubiquitination and degradation of p53, thereby activating the p53 pathway in p53 wild-type cells. Siremadlin succinate can be used in the research of cutaneous melanoma.

Application

Products | Products > Disease Areas > Cancer | Products > Disease Areas > Melanoma | Products > Signaling Pathways > Apoptosis | Products > Research Areas > Cancer | Products > Research Areas > Cancer > Cancer Targeted Therapy | Products > Research Areas > Cancer > Cancer Immunotherapy | Products > Research Areas > Cancer > Cancer Metabolism and Metastasis | Products > Signaling Pathways > MDM-2/p53

Product Information

• Catalog No.: HY-18658B
• CAS No.: 1638193-48-2
• Molecular Formula: C30H30Cl2N6O8
• Molecular Weight: 673.50
• Storage: Please store the product under the recommended conditions in the Certificate of Analysis.

Source

Original product source