Gangaleoidin

Overview

Gangaleoidin is a FOXM1 inhibitor with an IC 50 of 2.8 μM . Gangaleoidin inhibits interaction between FOXM1 ’s DNA-binding domain and target DNA sequence, downregulates FOXM1 and downstream target gene CCNB1 at the transcriptional level . Gangaleoidin suppresses proliferation of FOXM1 -overexpressing breast cancer cells . Gangaleoidin can be used for the research of breast cancer .

Application

Products | Products > Disease Areas > Cancer | Products > Disease Areas > Breast Cancer | Products > Signaling Pathways > Metabolic Enzyme/Protease | Products > Signaling Pathways > Cell Cycle/DNA Damage | Products > Research Areas > Cancer > Cancer Metabolism and Metastasis | Products > Research Areas > Cancer | Products > Research Areas > Cancer > Cancer Targeted Therapy | Products > Signaling Pathways > FOXM1 | Products > Signaling Pathways > DNA/RNA Synthesis

Product Information

• Catalog No.: HY-N19821
• CAS No.: 55365-63-4
• Molecular Formula: C18H14Cl2O7
• Molecular Weight: 413.21
• Storage: Please store the product under the recommended conditions in the Certificate of Analysis.

Source

Original product source