Guavenoic acid is a triterpenoid compound that can be isolated from fresh leaves of Psidium guajava . Guavenoic acid protects cells in cellular oxidative damage models, inhibits intracellular ROS production, and suppresses cell apoptosis . Guavenoic acid significantly enhances cellular proliferation, promotes insulin synthesis and secretion, and upregulates the messenger RNA expression of insulin gene, PDX-1 and MafA . Guavenoic acid can be used in the research of diseases such as pancreatic islet β-cell tumors.
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