2-Hydroxymelatonin

Overview

2-Hydroxymelatonin is a major hydroxylated metabolite of Melatonin ( HY-B0075 ). It is enzymatically produced in plants by melatonin 2-hydroxylase ( M2H/AsMT ), while in animals , it is generated in trace amounts via CYP450 or spontaneous oxidation. 2-Hydroxymelatonin acts as a respiratory burst oxidase homolog (RBOH)-dependent ROS burst inducer, thereby regulating stress tolerance, seed germination and growth in plants . In animal cells, 2-Hydroxymelatonin synergizes with BMP-4 to promote osteogenesis, and exerts pro- apoptotic and anti-metastatic activities against colorectal cancer cells. 2-Hydroxymelatonin can be used in studies related to plant premature senescence, osteoporosis and colorectal cancer .

Application

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Product Information

• Catalog No.: HY-N9409
• CAS No.: 229018-17-1
• Molecular Formula: C13H16N2O3
• Molecular Weight: 248.28
• Storage: Store at room temperature, keep dry and cool. In solvent -80°C, 1 year , -20°C, 6 months
• Availability: In-stock

Source

Original product source