Inotilone

Overview

Inotilone is an inhibitor of matrix metalloproteinase MMP-2 and MMP-9 , to against metastatic in lung cancer cells. Inotilone enhances the activity of the antioxidant enzymes to support its anti-metastatic activity. Inotilone also inhibits IκBα phosphorylation and NFκB p65 nuclear translocation, involving in FAK , PI3K/AKT, MAPKs and NFκB pathways.

Application

Products | Products > Signaling Pathways > Metabolic Enzyme/Protease | Products > Signaling Pathways > NF-κB | Products > Research Areas > Cancer | Products > Research Areas > Cancer > Cancer Targeted Therapy | Products > Research Areas > Cancer > Cancer Immunotherapy | Products > Research Areas > Cancer > Cancer Metabolism and Metastasis | Products > Signaling Pathways > MMP | Products > Signaling Pathways > NF-κB

Product Information

• Catalog No.: HY-111172
• CAS No.: 906366-79-8
• Molecular Formula: C12H10O4
• Molecular Weight: 218.21
• Purity: 95.26%
• Storage: 4°C, stored under nitrogen * In solvent : -80°C, 6 months; -20°C, 1 month (stored under nitrogen)
• Availability: In-stock

Source

Original product source