AKOS-22

AKOS-22
  • CAS No.:878983-38-1
  • Grade:99.23%
  • Formula:C22H21ClF3N3O3
  • M.W.:467.87
  • Solvent:≥ 2.08 mg/mL (4.45 mM); Clear solution

Overview

AKOS-22 is a potent mitochondrial protein VDAC1 (voltage-dependent anion channel 1) inhibitor ( K d =15.4 μM). AKOS-22 interacts with VDAC1 and inhibiting both VDAC1 oligomerization and apoptosis . AKOS-22 protects against mitochondrial dysfunction.

Application

Products | Products > Disease Areas > Neurodegenerative Disease | Products > Disease Areas > Digestive System Inflammation | Products > Disease Areas > Parkinson's Disease | Products > Disease Areas > Neurological, Eye or Ear Disease | Products > Disease Areas > Inflammation or Immune System Disease | Products > Disease Areas > Cancer | Products > Disease Areas > Digestive System Disease | Products > Signaling Pathways > Membrane Transporter/Ion Channel | Products > Signaling Pathways > Metabolic Enzyme/Protease | Products > Research Areas > Neurological Disease | Products > Research Areas > Cancer | Products > Research Areas > Cancer > Cancer Targeted Therapy | Products > Research Areas > Cancer > Cancer Metabolism and Metastasis | Products > Signaling Pathways > VDAC | Products > Signaling Pathways > Mitochondrial Metabolism

Product Information

  • Catalog No.: HY-111217
  • CAS No.: 878983-38-1
  • Molecular Formula: C22H21ClF3N3O3
  • Molecular Weight: 467.87
  • Purity: 99.23%
  • Storage: Powder -20°C, 3 years , 4°C, 2 years ; In solvent -80°C, 6 months , -20°C, 1 month
  • Solubility: ≥ 2.08 mg/mL (4.45 mM); Clear solution
  • Availability: In-stock

Source

Original product source


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