(R)-MK-8353 ((R)-SCH900353) is the R-enantiomer of MK-8353 ( HY-111407 ). MK-8353 (SCH900353) is a potent, selective and orally active ERK1 and ERK2 inhibitor with IC 50 s of 23.0 nM and 8.8 nM, respectively.
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