Bragsin1

Overview

Bragsin1 is a potent, selective and noncompetitive inhibitor of the ArfGEF BRAG2 , inhibits Arf GTPase activation, with an IC 50 of 3 μM. Bragsin1 binds to PH domain of BRAG2, and is a noncompetitive interfacial inhibitor. Bragsin1 has no effect on the Sec7 domain of human ArfGEFs. Anti-cancer activity.

Application

Products | Products > Disease Areas > Cancer | Products > Signaling Pathways > GPCR/G Protein | Products > Research Areas > Cancer | Products > Research Areas > Cancer > Cancer Targeted Therapy | Products > Research Areas > Cancer > Cancer Metabolism and Metastasis | Products > Signaling Pathways > Arf Family GTPase

Product Information

• Catalog No.: HY-111549
• CAS No.: 369631-68-5
• Molecular Formula: C11H6F3NO4
• Molecular Weight: 273.16
• Purity: 99.91%
• Storage: Powder -20°C, 3 years , 4°C, 2 years ; In solvent -80°C, 2 years , -20°C, 1 year
• Solubility: ≥ 2.08 mg/mL (7.61 mM); Clear solution
• Availability: In-stock

Source

Original product source