5-Iodo-indirubin-3'-monoxime

Overview

5-Iodo-indirubin-3'-monoxime is a potent GSK-3β , CDK5/P25 and CDK1/cyclin B inhibitor, competing with ATP for binding to the catalytic site of the kinase, with IC 50 s of 9, 20 and 25 nM, respectively.

Application

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Product Information

• Catalog No.: HY-111930
• CAS No.: 331467-03-9
• Molecular Formula: C16H10IN3O2
• Molecular Weight: 403.17
• Purity: 98.12%
• Storage: Powder -20°C, 3 years , 4°C, 2 years ; In solvent -80°C, 2 years , -20°C, 1 year
• Solubility: ≥ 2.25 mg/mL (5.58 mM); Clear solution
• Availability: In-stock

Source

Original product source