Cdk1/2 Inhibitor III

Overview

Cdk1/2 Inhibitor III (compound 3n) is a highly potent and selective Cdk1/cyclin B and Cdk2/cyclin A inhibitor of with IC 50 s of 0.6 nM and 0.5 nM, respectively. Cdk1/2 Inhibitor III shows selectivity over VEGF-R2 (IC 50 of 32 nM), GSK-3β (IC 50 of 140 nM), and a other kinases. Cdk1/2 Inhibitor III inhibits in cell proliferation with IC 50 s of 20 nM, 35 nM and 92 nM for HCT-116, HeLa, and A375 cells, respectively.

Application

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Product Information

• Catalog No.: HY-112462
• CAS No.: 443798-55-8
• Molecular Formula: C15H13F2N7O2S2
• Molecular Weight: 425.44
• Purity: 99.69%
• Storage: Powder -20°C, 3 years , 4°C, 2 years ; In solvent -80°C, 6 months , -20°C, 1 month
• Availability: In-stock

Source

Original product source