H-8 dihydrochloride

Overview

H-8 dihydrochloride is a selective Cyclic nucleotide-dependent protein kinase inhibitor. H-8 dihydrochloride potently inhibits cGMP- and cAMP-dependent protein phosphorylation. H-8 dihydrochloride enhances the vasodilatory effect induced by 8-bromo-cAMP ( HY-12306A ). H-8 dihydrochloride fails to attenuate the vasodilatory effects induced by 8-bromo-cGMP ( HY-101379A ), atrial natriuretic peptide II, or Sodium nitroprusside ( HY-B0564 ) in rat aorta.

Application

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Product Information

• Catalog No.: HY-112465
• CAS No.: 113276-94-1
• Molecular Formula: C12H17Cl2N3O2S
• Molecular Weight: 338.25
• Purity: 99.19%
• Storage: -20°C, sealed storage, away from moisture * In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)
• Solubility: ≥ 2.5 mg/mL (7.39 mM); Clear solution
• Availability: In-stock

Source

Original product source