Tivozanib hydrate (AV-951 hydrate; KRN951 hydrate) is the hydrate form of Tivozanib ( HY-10977 ). Tivozanib hydrate is a selective, orally active inhibitor for vascular endothelial growth factor receptor ( VEGFR )-1, 2 3, with IC 50 s of 30, 6.5 and 15 nM, respectively. Tivozanib hydrate exhibits antitumor efficacy.
Products | Products > Signaling Pathways > Protein Tyrosine Kinase/RTK | Products > Research Areas > Cancer | Products > Research Areas > Cancer > Cancer Targeted Therapy | Products > Signaling Pathways > VEGFR
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