RETRA hydrobromide

Overview

RETRA (hydrobromide) is a mutant p53-dependent activator of p73 that can inhibit cancer cells carrying mutant p53. RETRA (hydrobromide) increases the expression level of p73 , induces transcriptional activation of several common to transcriptional targets p53 and p73 , which leads to mutant p53- and p73 -dependent inhibition of tumor growth, reduction of colony formation and induction of effector caspases.

Application

Products | Products > Signaling Pathways > Apoptosis | Products > Research Areas > Cancer | Products > Research Areas > Cancer > Cancer Targeted Therapy | Products > Research Areas > Cancer > Cancer Metabolism and Metastasis | Products > Signaling Pathways > MDM-2/p53

Product Information

• Catalog No.: HY-113843
• CAS No.: 1035875-01-4
• Molecular Formula: C11H12BrNO3S2
• Molecular Weight: 350.25
• Purity: 99.98%
• Storage: Please store the product under the recommended conditions in the Certificate of Analysis.

Source

Original product source