MLS-573151 (MLS000573151) is a selective GTPase Cdc42 inhibitor with an EC 50 of 2 μM. MLS-573151 is inactive against other GTPases family members, such as Rab2, Rab7, H-Ras , Rac1, Rac 2 and RhoA wild-type. MLS-573151 acts by blocking the binding of GTP to Cdc42.
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