Onalespib lactate

Overview

Onalespib lactate is a potent and cross the blood-brain barrier heat-shock-protein-90 ( Hsp90 ) inhibitor with an K d value of 0.71 nM. Onalespib lactate inhibits the proliferation, survival and migration. Onalespib lactate decreases the expression of EGFR , p-EGFR, AKT , P-AKT, ERK1/2, P-ERK1/2, S6, P-S6 protein. Onalespib lactate shows antitumor activity. Onalespib lactate has the potential for the research of non-small cell lung cancer (NSCLC).

Application

Products | Products > Signaling Pathways > Cell Cycle/DNA Damage | Products > Signaling Pathways > Metabolic Enzyme/Protease | Products > Research Areas > Cancer | Products > Research Areas > Cancer > Cancer Targeted Therapy | Products > Research Areas > Cancer > Cancer Metabolism and Metastasis | Products > Signaling Pathways > HSP

Product Information

• Catalog No.: HY-113916
• CAS No.: 1019889-35-0
• Molecular Formula: C27H37N3O6
• Molecular Weight: 499.60
• Purity: 99.98%
• Storage: Please store the product under the recommended conditions in the Certificate of Analysis.

Source

Original product source