Z62954982

Overview

Z62954982 (ZINC08010136) is a potent, selective and cell-permeable Rac1 ( IC 50 =12 μM) inhibitor that is 4 times more effective than NSC23766 ( HY-15723A ) ( IC 50 =50 μM). Z62954982 disrupts the Rac1/Tiam1 complex and decreases cytoplasmic levels of active Rac1 (GTP-bound Rac1), without affecting the activity of other Rho GTPases (such as Cdc42 or RhoA).

Application

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Product Information

• Catalog No.: HY-115376
• CAS No.: 1090893-12-1
• Molecular Formula: C20H21N3O5S
• Molecular Weight: 415.46
• Purity: 99.38%
• Storage: Powder -20°C, 3 years ; In solvent -80°C, 6 months , -20°C, 1 month
• Solubility: 1.43 mg/mL (3.44 mM); Clear solution; Need ultrasonic
• Availability: In-stock

Source

Original product source