(Z)-NMac1

Overview

(Z)-NMac1 is an Nm23-H1 activator found in Zingiber cassumunar Roxb . (Z)-NMac1 has dual anti-metastatic and anti-proliferative biological activities. (Z)-NMac1 selectively inhibits cancer cell proliferation under glucose starvation conditions by inhibiting mitochondrial complex I activity, leading to ATP depletion and mitochondrial dysfunction. (Z)-NMac1 can be used to study tumors with high oxidative phosphorylation , especially in the glucose-restricted tumor microenvironment.

Application

Products | Products > Signaling Pathways > Metabolic Enzyme/Protease | Products > Research Areas > Cancer | Products > Research Areas > Cancer > Cancer Metabolism and Metastasis | Products > Signaling Pathways > Oxidative Phosphorylation | Products > Signaling Pathways > Mitochondrial Metabolism

Product Information

• Catalog No.: HY-115507A
• CAS No.: 1667730-59-7
• Molecular Formula: C24H28O4
• Molecular Weight: 380.48
• Purity: 99.98%
• Storage: Please store the product under the recommended conditions in the Certificate of Analysis.
• Availability: In-stock

Source

Original product source